Deficiency of thiamine can manifest as mental confusion, muscle weakness, indigestion, constipation, and other more serious conditions. Causes for deficiency include malnutrition, genetic polymorphisms, and excessive consumption of caffeine and alcohol.

The B vitamins are essential for healthy nerve cell function &ndash especially thiamine, folate, and vitamin B12.

Thorne's B-Complex #1 supplies 200 mg of thiamine HCl and the bioactive forms of the other B vitamins in each capsule to ensure you get the most bioavailable B-complex available.

B-Complex #1 consists of a group of eight water-soluble compounds: thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), pantothenic acid (vitamin B5), pyridoxine (vitamin B6), cobalamin (vitamin B12), folate, and biotin. Although each B vitamin is chemically distinct, they often work together in various biochemical functions throughout the body - from cellular energy production, to healthy red-blood-cell formation, to healthy neurological function. Most B vitamins, with the exception of vitamin B12, are not stored in the body; consequently, they must be acquired daily from the diet in order to maintain optimal health.

Supplementing with active B vitamins is extremely important to everyone, especially individuals who may not be able to convert non-active vitamins to their active forms in the liver because of compromised liver function, poorly functioning enzymes, digestive disturbances, or age. Dietary supplements containing these active cofactors have enhanced bioavailability, ensuring the body gets the nutrients it needs.